Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKbeta/NF-kappaB signaling pathway in lung cancer cells

ExpressionData

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Source: ExpressionData

Dynamic cluster scheduling for cluster-tree WSNs

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Source: Dynamic cluster scheduling for cluster-tree WSNs

A novel approach for the discovery of chemically diverse anti-malarial compounds targeting the Plasmodium falciparum Coenzyme A synthesis pathway

Allantoin activates imidazoline I-3 receptors to enhance insulin secretion in pancreatic beta-cells

Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKbeta/NF-kappaB signaling pathway in lung cancer cells

Gamabufotalin (CS-6), a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic stability and less adverse effect. However, the underlying mechanism of CS-6 involved in anti-tumor activity remains poorly understood. Methods: The biological functions of…
Source:Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKbeta/NF-kappaB signaling pathway in lung cancer cells

Blind loop: rare but important surgical complication

Surgical complications worldwide are dreaded by both patients and physicians alike and represent significant and serious morbidity and mortality, and contribute substantially to increased costs of healthcare. Case presentation: Our Case Report describes a 65yo Caucasian man with an extensive…
Source:Blind loop: rare but important surgical complication

Axillary and rectal thermometry in the newborn: do they agree?

Accurate measurement of body temperature is critical for the assessment of a newborn’s general well-being. In nursery settings, the gold standard rectal thermometry has been replaced by the axillary method. However, evidence pertaining to the agreement between axillary and rectal…
Source:Axillary and rectal thermometry in the newborn: do they agree?

Patient, surgeon, and healthcare purchaser views on the use of decision and communication aids in orthopaedic surgery: a mixed methods study

Despite evidence that decision and communication aids are effective for enhancing the quality of preference-sensitive decisions, their adoption in the field of orthopaedic surgery has been limited. The purpose of this mixed-methods study was to evaluate the perceived value of decision and…
Source:Patient, surgeon, and healthcare purchaser views on the use of decision and communication aids in orthopaedic surgery: a mixed methods study

High-resolution melting analysis reveals genetic polymorphisms in MicroRNAs confer hepatocellular carcinoma risk in Chinese patients

Although several single-nucleotide polymorphisms in microRNA (miRNA) genes have been associated with primary hepatocellular carcinoma, published findings regarding this relationship are inconsistent and inconclusive. Methods: The high-resolution melting (HRM) analysis was used to determine…
Source:High-resolution melting analysis reveals genetic polymorphisms in MicroRNAs confer hepatocellular carcinoma risk in Chinese patients

Sunbed study highlights cancer risk

31 August 2014 Last updated at 00:28 The study looked at UV levels, length of session, number of sessions and exposure to sun Sunbed users are still at risk of skin cancer even if they do not burn their skin, according to a new study. Researchers found sunbeds significantly…
Source:Sunbed study highlights cancer risk

'Urgent' call for obesity taskforce

31 August 2014 Last updated at 03:14 Health leaders are calling for an emergency taskforce to be set up to tackle childhood obesity in England. In an open letter to the chief medical officer for England, Prof Dame Sally Davies, they say “an entire generation is being…
Source:'Urgent' call for obesity taskforce

A pan-Theileria FRET-qPCR survey for Theileria spp. in ruminants from nine provinces of China

High-resolution melting analysis reveals genetic polymorphisms in MicroRNAs confer hepatocellular carcinoma risk in Chinese patients

Patient, surgeon, and healthcare purchaser views on the use of decision and communication aids in orthopaedic surgery: a mixed methods study